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Related Articles Stem Cells: Biology and Promise for Regenerative Medicine, Elaine Fuchs

General Reading

Scratching the surface of skin development. Fuchs E. Nature 445, 834-842 (2007). Reik, W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447:425-32 (2007). Turning over new leaves: epithelial stem cells. Blanpain C, Horsley V and Fuchs E. Cell 128, 445-458 (2007). Lindvall O, Kokaia Z. Stem cells for the treatment of neurological disorders. Nature 441:1094-6 (2007). Epidermal stem cells of the skin. Blanpain C, Fuchs E. Ann Rev Cell Dev Biol 22, 339-373 (2006). Intermediate filaments in morphogenesis & disease. Cleveland DW, Fuchs E. Science 279, 514-19 (1998).

Additional Reading

Mice cloned from skin cells. Li J, Greco V, Guasch G, Fuchs E, Mombaerts P. PNAS USA 104, 2738-44 (2007). Blimp1 defines a novel progenitor population that governs cellular input to the sebaceous gland, Horsley V, O’Carroll D, Tooze R, Ohinata Y, Saitou M, Obukhanych T, Nussenzweig M, Tarakhovsky A, Fuchs E. Cell 126, 597-609 (2006). Lhx2 maintains stem cell character in hair follicles. Rhee H, Polak L, Fuchs E. Science 312,1946-49 (2006). Asymmetric cell divisions promote stratification and differentiation of mammalian skin, Lechler T & Fuchs E. Nature 437, 275-280 (2005). Molecular dissection of mesenchymal-epithelial interactions in the hair follicle, Rendl M, Lewis L & Fuchs E. PLoS Biology 3, 1910-1924 (2005). Defining the impact of ß-catenin/Tcf transactivation on epithelial stem cells Lowry WE, Blanpain C, Nowak J, Guasch G, Lewis L, Fuchs E. Genes Dev 19, 1596-1611 (2005). Self renewal, multipotency and the existence of two cell populations within an epithelial stem cell niche. Blanpain, C, Lowry W.E, Geoghegan A, Polak, L, Fuchs E. Cell 118, 635-648 (2004). Socializing with the neighbors: stem cells & their niches. Fuchs E, Tumbar T, Guasch G. Cell 116 769-78 (2004). Defining the epithelial stem cell niche of the skin. Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M, Polak L, Fuchs E. [Science Express Dec 11, 2003] Science 303, 359-363 (2004). At the roots of a never-ending cycle. Fuchs E, Merrill B, DasGupta R. Dev Cell 1,13-26 (2001). A common human skin tumor is caused by activating mutations in beta-catenin, Chan EF, Gat U, McNiff J, Fuchs E. Nature Genetics 21, 410-413, 1999. De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated ß-catenin in skin. Gat U, DasGupta R, Degenstein L, Fuchs E. Cell, 95, 605-614 (1998).

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