Yang et al. created an intraflagellar transport 27 (ift27) knockout mouse, which led to disrupted ciliogenesis, but maintained the ciliary axoneme. They found that this led to attenuated hedgehog signaling during hair follicle morphogenesis, suggesting that Hh signaling can be segregated from the ciliary machinery. Published in Development.
As part of its fundamental commitment to transparency and reproducibility in science, the ASCB has added its official signature to that of 34 other scientific organizations, endorsing the Center for Open Science’s new Transparency and Openness Promotion (TOP) Guidelines. In addition, ASCB’s journals, Molecular Biology of the Cell and CBE-Life Sciences Education, have joined 111…Details
Lee et. al. found that CXXC-type zinc finger protein 5 (CXXC5) acts as a negative feedback regulator of a wound healing pathway. They generated CXXC5−/− mice, which exhibited accelerated wound healing, and enhanced keratin and collagen synthesis. Published in Journal of Experimental Medicine.
Schuster and Smith-Bolton have a model for regeneration in which they identified a gene (taranis) required for maintaining cell fate in damaged and regenerating Drosophila wing discs, which is not required for cell fate in normal wing development. Published in Developmental Cell.
Köberlin et al. investigated the regulatory role of membrane lipid composition in Toll-Like Receptor (TLR) signaling. They found that sphingolipid metabolism regulates TLR signaling, trafficking, and cytokine release, and that annotated lipid networks can predict TLR responses in patient cells. Published in Cell.
As we continue to launch the renovated Career Development website, we will be developing more content and resources to add to this networking page. However, until that content is available, we want to provide some initial information and resources for guidance. If you know of resources or content you think should be represented here, please…Details
As we continue to launch the renovated Career Development website, we will be adding to this list. If you know of resources or opportunities that should be represented here, please feel free to email me at email@example.com. Where can you find professional development opportunities? It is remarkably difficult to search for professional development opportunities, particularly affordable…Details
Scientific writing is one of the most essential skills in science. It’s critical for writing grants, good theses, and manuscripts, as well as for posters and presentations. Because it’s so crucial, we have assembled a collection of resources to help you learn how to, or refine your skills to, write (and review!) scientifically. No matter…Details