| Time (in ET) | Description |
|---|---|
| 10:30 – 10:35 AM | Welcome Remarks by Erika Holzbaur and Andrea Stavoe |
| 10:35 – 10:55 AM | Speaker: George Langford, Syracuse University |
| 10:55 – 11:25 AM | Speaker: Pietro De Camilli, Yale University |
| 11:25 – 11:55 AM | Speaker: Frank Bradke, German Center for Neurodegenerative Diseases |
| 11:55 – 12:05 PM | Break |
| 12:05 – 1:05 PM | Short Talks (Round 1): 12:05-12:11pm Nuclear accumulation of CHMP7 initiates nuclear pore complex injury in familial and sporadic ALS Alyssa Coyne, Johns Hopkins University School of Medicine 12:11-12:17pm Elucidating the Cellular Functions of Timm50, a Mitochondrial Transport Protein, in Neurons and Astrocytes Eyal Paz, Tel Aviv University 12:17-12:23pm Ribosome collisions fuel a vicious cycle of neurotoxicity in Huntington’s Disease Ranen Aviner, Stanford University 12:23-12:29pm ER stress-induced JNK promotes stress granule formation via epigenetic modifications in C9orf72 mediated ALS/FTD Sahana Gopalakrishna, Mayo Clinic 12:29-12:35pm Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9 Sisi Yang, Yale University 12:35-12:41pm Modulating Histone Modifications in ALS/FTD: New Avenues for Suppressing Toxicity of Neurodegenerative Disease Proteins Mariana Torrente, Brooklyn College/City University of New York 12:41-12:47pm SHIP164 is a Chorein Motif Containing Lipid Transport Protein that Controls Membrane Dynamics and Traffic at the Endosome-Golgi Interface Michael Hanna, Yale University 12:47-12:53pm ER network stability promotes organized microtubule disassembly during Compartmentalized Cell Elimination Piya Ghose, The University of Texas at Arlington 12:53-12:59pm Activation of the CaMKII-Sarm1-ASK1 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria Chen Ding, Yale University 12:59-1:05pm In Vitro Reconstituted Stress Granule-Like Condensates are Nucleation Sites for Aggregation of Misfolded Proteins Andrii Kopach, International Institute of Molecular and Cell Biology in Warsaw |
| 1:05 – 1:25 PM | Lunch & Networking (Round 1) Topic: Science |
| 1:25 – 1:45 PM | Lunch & Networking (Round 2) Topic: Science |
| 1:45 – 2:15 PM | Lunch & Networking (Round 3) Topic: Inclusion in Cell Biology |
| 2:15 – 3:15 PM | Short Talks (Round 2): 2:15pm – 2:21pm Mitochondria-lysosomes crosstalk alterations and neurodegeneration: Charcot-Marie-Tooth type 2B as the paradigm of nervous peripheral damage Flora Guerra, University of Salento 2:21pm – 2:27pm Phase Separation at the Synapse: Material Properties and Functional Implications Dragomir Milovanic, German Center for Neurodegenerative Diseases (DZNE) 2:27pm – 2:33pm Kinesin-13 regulates developmental pruning of dendrites in the PVD neurons of Caenorhabditis elegans Swagata Dey, National Brain Research Centre, Manesar, India 2:33pm – 2:39pm The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets Jeeyun Chung, Harvard University 2:39pm – 2:45pm Spastic paraplegia protein ortholog, reticulon-like 1, governs presynaptic ER organization and Ca2+ dynamics Rebecca Smith, University of Cambridge 2:45pm – 2:51pm DLK regulates mitochondrial fission by phosphorylating DRP1 after axonal injury Jorge Gomez Deza, National Institutes of Health 2:51pm – 2:57pm ApoE targets astrocyte cytoplasmic lipid droplets to modulate phosphatidylcholine metabolism and droplet size Ian Windham, University of North Carolina at Chapel Hill 2:57pm – 3:03pm Exploring The Role of the E3 Ubiquitin Ligase TRIM9 in Alzheimer’s Disease Charise White, University of North Carolina at Chapel Hill 3:03pm – 3:09pm TPPP Forms Liquid Condensates and Aggregates in Multiple System Atrophy Shahrnaz Kemal, National Institutes of Health 3:09pm – 3:15pm Insulin signaling enhances the anterograde speed of Rab4-associated vesicles in the cholinergic neurons of Drosophila Kamaldeep Singh, Tata Institute of Fundamental Research Mumbai, India |
| 3:15 – 3:25 PM | Break |
| 3:25 – 3:55 PM | Panel Session: Developing Therapeutic Approaches to Neurodegenerative Disease Shalini Padmanbhan, The Michael J. Fox Foundation for Parkinson’s Research Lucie Bruijn, AveXis, Inc. |
| 3:55 – 4:25 PM | Speaker: Ai Yamamoto, Columbia University |
| 4:25 – 4:55 PM | Speaker: Andrea Stavoe, UTHealth McGovern Medical School |
| 4:55 – 5:00 PM | Closing Remarks |
Program Chairs
| Erika Holzbaur William Maul Measey Professor of Physiology University of Pennsylvania Perelman School of Medicine | Andrea Stavoe Assistant Professor, Neurobiology and Anatomy University of Texas Health McGovern Medical School |