MBoC Publishes New Articles on Cell Biology of the Lysosome

ASCB’s scientific journal, Molecular Biology of the Cell (MBoC) is pleased to present its special collection on Cell Biology of the Lysosome.

Lead Editors

Michael S. Marks, Children’s Hospital of Philadelphia and University of Pennsylvania 
Sergio Grinstein, University of Toronto and Hospital for Sick Children 
Roberto Zoncu, University of California, Berkeley 
Sharon Tooze, The Francis Crick Institute 

Articles

• Stress-induced microautophagy is coordinated with lysosome biogenesis and regulated by PIKfyve
  Authors: Alison D. Klein, Kayla L. Petruzzi, Chan Lee, and Michael Overholtzer
• Reversible assembly and disassembly of V-ATPase during the lysosome regeneration cycle
  Authors: Ioana Sava, Luther J. Davis, Sally R. Gray, Nicholas A. Bright, and J. Paul Luzio
• Tepsin binds LC3B to promote ATG9A trafficking and delivery
  Authors: Natalie S. Wallace, John E. Gadbery, Cameron I. Cohen, Amy K. Kendall, and Lauren P. Jackson
• Lysosomal membrane proteins LAMP1 and LIMP2 are segregated in the Golgi apparatus independently of their clathrin adaptor binding motif
  Authors: Jason Ecard, Yen-Ling Lian, Séverine Divoux, Zelia Gouveia, Emmanuelle Vigne, Franck Perez, and Gaelle Boncompain
• Loss of the HOPS complex disrupts early-to-late endosome transition, impairs endosomal recycling and induces accumulation of amphisomes
  Authors: Jan van der Beek, Cecilia de Heus, Paolo Sanza, Nalan Liv, and Judith Klumperman
• The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes
  Authors: Lu Huang, Natalie W. Thiex, Jieqiong Lou, Gulzar Ahmad, Wei An, Shalini T. Low-Nam, Jason G. Kerkvliet, Hamid Band, and Adam D. Hoppe
• Ninein promotes F-actin cup formation and inward phagosome movement during phagocytosis in macrophages
  Authors: Safia Omer, Jiahao Li, Claire X. Yang, and Rene E. Harrison
• Lysosomal membrane transporter purification and reconstitution for functional studies
  Authors: Felichi Mae Arines, Aleksander Wielenga, Danielle Henn, Olive E. Burata, Francisco Narro Garcia, Randy B. Stockbridge, and Ming Li
• Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila
  Authors: Adriana Steinbach, Varun Bhadkamkar, David Jimenez-Morales, Erica Stevenson, Gwendolyn M. Jang, Nevan J. Krogan, Danielle L. Swaney, and Shaeri Mukherjee
• Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipids
  Authors: Inger Ødum Nielsen, Knut Kristoffer Bundgaard Clemmensen, Ditte Louise Fogde, Tiina Naumanen Dietrich, Jano Dicroce Giacobini, Mesut Bilgin, Marja Jäättelä, and Kenji Maeda
• Signaling pathways regulating the extracellular digestion of lipoprotein aggregates by macrophages
  Authors: Noah Steinfeld, Cheng-I J. Ma, and Frederick R. Maxfield
• Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence
  Authors: Sumaiya A. Soha, Araniy Santhireswaran, Saaimatul Huq, Jayde Casimir-Powell, Nicala Jenkins, Gregory K. Hodgson, Michael Sugiyama, Costin N. Antonescu, Stefania Impellizzeri, and Roberto J. Botelho