ASCB’s scientific journal, Molecular Biology of the Cell (MBoC) is pleased to present its special collection on Protein Quality Control.
Lead Editors
Elizabeth Miller, MRC Laboratory of Molecular Biology
Guillaume Thibault, Nanyang Technological University
Articles
- Characterization of hyperactive mutations in the renal potassium channel ROMK uncovers unique effects on channel biogenesis and ion conductance
Authors: Nga H. Nguyen, Shaohu Sheng, Anupam Banerjee, Christopher J. Guerriero, Jingxin Chen, Xueqi Wang,Timothy D. Mackie, Paul A. Welling, Thomas R. Kleyman, Ivet Bahar, Anne E. Carlson, and Jeffrey L. Brodsky - Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage
Authors: Jake W. Carrasquillo Rodríguez, Onyedikachi Uche, Shujuan Gao, Shoken Lee, Michael V. Airola, and Shirin Bahmanyar - Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations
Authors: Nicole Madrazo, Zinia Khattar, Evan T. Powers, Jessica D. Rosarda, and R. Luke Wiseman - Loss of Grp170 results in catastrophic disruption of endoplasmic reticulum function
Authors: Melissa J. Mann, Chris Melendez-Suchi, Hannah E. Vorndran, Maria Sukhoplyasova, Ashley R. Flory, Mary Carson Irvine, Anuradha R. Iyer, Christopher J. Guerriero, Jeffrey L. Brodsky, Linda M. Hendershot, and Teresa M. Buck - Cytoplasmic redox imbalance in the thioredoxin system activates Hsf1 and results in hyperaccumulation of the sequestrase Hsp42 with misfolded proteins
Authors: Davi Goncalves, Duong Long Duy, Sara Peffer, and Kevin A. Morano - The p24-family and COPII subunit SEC24C facilitate the clearance of alpha1-antitrypsin Z from the endoplasmic reticulum to lysosomes
Authors: Benjamin S. Roberts, Debashree Mitra, Sudhanshu Abishek, Richa Beher, and Prasanna Satpute-Krishnan - Small-molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states
Authors: Celeste Riepe, Magda Wąchalska, Kirandeep K. Deol, Anais K. Amaya, Matthew H. Porteus, James A. Olzmann, and Ron R. Kopito - Exploring the “misfolding problem” by systematic discovery and analysis of functional-but-degraded proteins
Authors: Matthew P. Flagg, Breanna Lam, Darren K. Lam, Tiffany M. Le, Andy Kao, Yousif I. Slaiwa, and Randolph Y. Hampton - Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding
Authors: Michela Ciccarelli, Anna E. Masser, Jayasankar Mohanakrishnan Kaimal, Jordi Planells, and Claes Andréasson - The unfolded protein response of the endoplasmic reticulum supports mitochondrial biogenesis by buffering nonimported proteins
Authors: Katharina Knöringer, Carina Groh, Lena Krämer, Kevin C. Stein, Katja G. Hansen, Jannik Zimmermann, Bruce Morgan, Johannes M. Herrmann, Judith Frydman, and Felix Boos
About the Author:
This post was collaboratively written by several ASCB staff members.
